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Tasuku Honjo

27 January 1942 – present

Tasuku Honjo is a Japanese immunologist and professor at Kyoto University. He identified the immune receptor PD-1 in 1992 and the enzyme activation-induced cytidine deaminase (AID), work that underpinned the development of cancer therapies based on immune checkpoint blockade. He shared the 2018 Nobel Prize in Physiology or Medicine with James P. Allison.

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Life events

Born in Kyoto, Japan
27 January 1942

Tasuku Honjo was born on 27 January 1942 in Kyoto.

Source: en.wikipedia.org
Birth ✓
Graduated from the Kyoto University Faculty of Medicine
1966

He received his medical degree from Kyoto University in 1966.

Source: en.wikipedia.org
Education ✓
Research fellowship in the United States
1971 – 1974

He worked at the Carnegie Institution of Washington and the National Institutes of Health in the early 1970s.

Source: en.wikipedia.org
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Awarded a PhD by Kyoto University
1975

He completed his doctorate in medical chemistry in 1975.

Source: en.wikipedia.org
Education ✓
Appointed professor at Osaka University
1979

He took a chair at the Osaka University School of Medicine in 1979.

Source: en.wikipedia.org
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Appointed professor at Kyoto University
1984

He returned to the Kyoto University Faculty of Medicine as a professor in 1984.

Source: en.wikipedia.org
Career ✓
Identified the immune receptor PD-1
1992

His laboratory reported programmed cell death protein 1 in 1992, later a target of checkpoint inhibitor drugs.

Source: en.wikipedia.org
Achievement ✓
Identified activation-induced cytidine deaminase (AID)
1999

His group described the enzyme required for antibody class switching and somatic hypermutation.

Source: en.wikipedia.org
Achievement ✓
Received the Kyoto Prize in Basic Sciences
2016

The Inamori Foundation awarded him the prize in 2016.

Source: en.wikipedia.org
Achievement ✓
Awarded the Nobel Prize in Physiology or Medicine
1 October 2018

He shared the 2018 prize with James P. Allison for the discovery of cancer therapy by inhibition of negative immune regulation.

Source: en.wikipedia.org
Achievement ✓